Vitiligo is a chronic depigmentary disorder of the skin resulting from the destruction of melanocytes. It poses therapeutic challenges in conventional medicine, where outcomes are often temporary and unsatisfactory. Homoeopathy, through individualization, aims to address both the disease and the patient’s sleep is normal. This case report presents the successful treatment of vitiligo in an adolescent male with Calcarea phosphorica as the individualized prescription and Tuberculinum as an intercurrent remedy, selected based on miasmatic background