Abstract: Corona virus is a Novel RNA Virus member of the family Coronaviridae it causes Diseases in mammals and birds, In humans it causes respiratory tract infections It is First discovered in 1930 at North Dakota in domesticated chickens with New Respiratory Infection infectious bronchitis virus (IBV). In present review work Research conducting on latest case study on Corona virus (COVID-19) outbreak at Wuhan city of China in December 2019.