Synthesis and antiviral activity of 2-3,5 dinitropheny1-5-substituted phenyl 1,3,4-oxadiazoles
Author(s): Dr. Archana Jyoti
Abstract: 3, 5 dinitro benzoic acid hydrazide was prepared by the hydrazinolysis of the corresponding ethyl ester. Condensation of this hydrazide with different aromatic acids in presence of POCl3 gave 2-3, 5 dinitropheny1-5-substituted pheny1 1, 3, 4-oxadiazoles. All the final compounds were tested against Ranikhet Disease Virus (RDV). However no compound showed antiviral activity against RDV.